Issue 44, 2014

Enzymatic preparation of a redox-responsive hydrogel for encapsulating and releasing living cells

Abstract

Horseradish peroxidase-mediated oxidative cross-linking of a thiolated poly(ethylene glycol) is promoted in the absence of exogenous hydrogen peroxide, by adding a small amount of a phenolic compound under physiological conditions. The prepared hydrogel can encapsulate and release living mammalian cells.

Graphical abstract: Enzymatic preparation of a redox-responsive hydrogel for encapsulating and releasing living cells

Supplementary files

Article information

Article type
Communication
Submitted
25 Dec 2013
Accepted
23 Mar 2014
First published
24 Apr 2014

Chem. Commun., 2014,50, 5895-5898

Author version available

Enzymatic preparation of a redox-responsive hydrogel for encapsulating and releasing living cells

K. Moriyama, K. Minamihata, R. Wakabayashi, M. Goto and N. Kamiya, Chem. Commun., 2014, 50, 5895 DOI: 10.1039/C3CC49766F

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