Issue 15, 2014

Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis

Abstract

Current strategies for the synthesis of glycopeptides require multiple manual synthetic steps. Here, we describe a synthesis concept that merges solid phase peptide and oligosaccharide syntheses and can be executed automatically using a single instrument.

Graphical abstract: Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis

Supplementary files

Article information

Article type
Communication
Submitted
16 Nov 2013
Accepted
11 Dec 2013
First published
17 Dec 2013

Chem. Commun., 2014,50, 1851-1853

Author version available

Automated glycopeptide assembly by combined solid-phase peptide and oligosaccharide synthesis

M. Hurevich and P. H. Seeberger, Chem. Commun., 2014, 50, 1851 DOI: 10.1039/C3CC48761J

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