Issue 10, 2014

Room-temperature Pd-catalyzed C–H chlorination by weak coordination: one-pot synthesis of 2-chlorophenols with excellent regioselectivity

Abstract

A room-temperature Pd(II)-catalyzed regioselective chlorination reaction has been developed for a facile one-pot synthesis of a broad range of 2-chlorophenols. The reaction demonstrates an excellent regioselectivity and reactivity for C–H chlorination. This reaction represents one of the rare examples of mild C–H functionalization at ambient temperature.

Graphical abstract: Room-temperature Pd-catalyzed C–H chlorination by weak coordination: one-pot synthesis of 2-chlorophenols with excellent regioselectivity

Supplementary files

Article information

Article type
Communication
Submitted
29 Sep 2013
Accepted
24 Nov 2013
First published
26 Nov 2013

Chem. Commun., 2014,50, 1262-1264

Room-temperature Pd-catalyzed C–H chlorination by weak coordination: one-pot synthesis of 2-chlorophenols with excellent regioselectivity

X. Sun, Y. Sun, C. Zhang and Y. Rao, Chem. Commun., 2014, 50, 1262 DOI: 10.1039/C3CC47431C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements