Issue 99, 2013

Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNA

Abstract

A unique system has been developed for quantifying G-quadruplex forming DNA down to picomolar levels for future applications in telomeric assessment. Pyrene-imidazolium captured in high amounts on the surface of reduced graphene oxide shells allows specific DNA sequence detection by complex formation resulting in release and fluorescence enhancement of pyrene-imidazolium.

Graphical abstract: Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNA

Supplementary files

Article information

Article type
Communication
Submitted
04 Sep 2013
Accepted
22 Oct 2013
First published
22 Oct 2013

Chem. Commun., 2013,49, 11698-11700

Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNA

S. J. Moon, S. H. Park, J. Jaworski and J. H. Jung, Chem. Commun., 2013, 49, 11698 DOI: 10.1039/C3CC46744A

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