Issue 85, 2013

Metallo-toeholds: controlling DNA strand displacement driven by Hg(ii) ions

Abstract

Toehold-mediated strand displacement is a powerful tool that permits programmable control over DNA hybridization. Here, we developed a mechanism for strand displacement driven by Hg2+ ions, in which the insertion of thymine–thymine mismatched base pairs on the toeholds provides additional control through variation of the concentration of Hg2+ ions.

Graphical abstract: Metallo-toeholds: controlling DNA strand displacement driven by Hg(ii) ions

Supplementary files

Article information

Article type
Communication
Submitted
16 Jul 2013
Accepted
27 Aug 2013
First published
28 Aug 2013

Chem. Commun., 2013,49, 9953-9955

Metallo-toeholds: controlling DNA strand displacement driven by Hg(II) ions

W. Ding, W. Deng, H. Zhu and H. Liang, Chem. Commun., 2013, 49, 9953 DOI: 10.1039/C3CC45373A

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