Design, synthesis and evaluation of a boronic acid based artificial receptor for l-DOPA in aqueous media†
Abstract
Design and synthesis of a boronic acid based artificial receptor which selectively and effectively bound to a neurotransmitter, L-DOPA (1), in aqueous media. In addition, the synthetic receptor was found to effectively inhibit the DDC (L-DOPA decarboxylase) enzymatic reaction under physiological conditions.