Issue 72, 2013
From the journal:

Chemical Communications

Ultrasensitive dual-channel detection of matrix metalloproteinase-2 in human serum using gold-quantum dot core–satellite nanoprobes†

Tingting Zheng,ab   Rui Zhang,a   Qingfeng Zhang,b   Tingting Tan,c   Kui Zhang,c   Jun-Jie Zhu*a  and  Hui Wang*b  

* Corresponding authors

a State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210093, China
E-mail: jjzhu@nju.edu.cn

b Department of Chemistry and Biochemistry, University of South Carolina, 631 Sumter Street, Columbia, South Carolina 29208, USA
E-mail: wang344@mailbox.sc.edu

c Department of Medical Laboratory, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, China

Abstract

We have developed a robust enzymatic peptide cleavage-based assay for the ultrasensitive dual-channel detection of matrix metalloproteinase-2 (MMP-2) in human serum using gold-quantum dot (Au-QD) core–satellite nanoprobes.

Graphical abstract: Ultrasensitive dual-channel detection of matrix metalloproteinase-2 in human serum using gold-quantum dot core–satellite nanoprobes

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Article information

DOI
https://doi.org/10.1039/C3CC44623A
Article type
Communication
Submitted
20 Jun 2013
Accepted
11 Jul 2013
First published
11 Jul 2013

Chem. Commun., 2013,49, 7881-7883

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Ultrasensitive dual-channel detection of matrix metalloproteinase-2 in human serum using gold-quantum dot core–satellite nanoprobes

T. Zheng, R. Zhang, Q. Zhang, T. Tan, K. Zhang, J. Zhu and H. Wang, Chem. Commun., 2013, 49, 7881 DOI: 10.1039/C3CC44623A

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