Issue 82, 2013

G-quadruplex unfolding in higher-order DNA structures

Abstract

G-quadruplex unfolding within a sequence of two quadruplex units was characterized by gel electrophoresis, calorimetry and spectroscopy. The obtained results suggest that the kinetics and thermodynamics of the individual quadruplex unfolding are affected by its interaction with other DNA secondary structural elements.

Graphical abstract: G-quadruplex unfolding in higher-order DNA structures

Supplementary files

Article information

Article type
Communication
Submitted
18 Jun 2013
Accepted
16 Aug 2013
First published
19 Aug 2013

Chem. Commun., 2013,49, 9488-9490

G-quadruplex unfolding in higher-order DNA structures

I. Fotticchia, C. Giancola and L. Petraccone, Chem. Commun., 2013, 49, 9488 DOI: 10.1039/C3CC44560G

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