Issue 79, 2013
From the journal:

Chemical Communications

A novel approach for the one-pot preparation of α-ketoamides by anodic oxidation†

Zhenlei Zhang,‡a   Jihu Su,‡b   Zhenggen Zha*a  and  Zhiyong Wang*a  

* Corresponding authors

a Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry and Department of Chemistry, Univ Sci & Technol China, Hefei, Anhui, P. R. China
E-mail: zwang3@ustc.edu.cn
Fax: +86-551-3603185

b Hefei National Laboratory for Physical Sciences at Microscale and Department of Modern Physics, Univ Sci & Technol China, Hefei, Anhui, P. R. China

Abstract

The direct oxidative synthesis of α-ketoamides via anodic oxidation was developed by using dioxygen as a reactant under mild conditions. This methodology has a broad substrate scope (aromatic amines, aliphatic amines and ammonium acetate) and opens up an interesting and attractive avenue for the synthesis of α-ketoamide derivatives.

Graphical abstract: A novel approach for the one-pot preparation of α-ketoamides by anodic oxidation

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Article information

DOI
https://doi.org/10.1039/C3CC43685C
Article type
Communication
Submitted
16 May 2013
Accepted
26 Jul 2013
First published
31 Jul 2013

Chem. Commun., 2013,49, 8982-8984

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A novel approach for the one-pot preparation of α-ketoamides by anodic oxidation

Z. Zhang, J. Su, Z. Zha and Z. Wang, Chem. Commun., 2013, 49, 8982 DOI: 10.1039/C3CC43685C

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