Issue 66, 2013
From the journal:

Chemical Communications

An ultrasensitive electrochemical aptasensor with autonomous assembly of hemin–G-quadruplex DNAzyme nanowires for pseudo triple-enzyme cascade electrocatalytic amplification†

Yali Yuan,a   Yaqin Chai,*a   Ruo Yuan,*a   Ying Zhuoa  and  Xianxue Gana  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China
E-mail: yuanruo@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68252277

Abstract

We for the first time fabricate a pseudo triple-enzyme cascade electrocatalytic electrochemical aptasensor by using the alcohol dehydrogenase (ADH) as well as the autonomously assembled hemin–G-quadruplex that simultaneously acted as an NADH oxidase and HRP-mimicking DNAzyme.

Graphical abstract: An ultrasensitive electrochemical aptasensor with autonomous assembly of hemin–G-quadruplex DNAzyme nanowires for pseudo triple-enzyme cascade electrocatalytic amplification

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Article information

DOI
https://doi.org/10.1039/C3CC42874E
Article type
Communication
Submitted
18 Apr 2013
Accepted
12 Jun 2013
First published
12 Jun 2013

Chem. Commun., 2013,49, 7328-7330

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An ultrasensitive electrochemical aptasensor with autonomous assembly of hemin–G-quadruplex DNAzyme nanowires for pseudo triple-enzyme cascade electrocatalytic amplification

Y. Yuan, Y. Chai, R. Yuan, Y. Zhuo and X. Gan, Chem. Commun., 2013, 49, 7328 DOI: 10.1039/C3CC42874E

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