Issue 44, 2013

Synthesis of substituted hydantoins in low melting mixtures

Abstract

A novel domino synthesis of 1,3,5-trisubstituted hydantoin derivatives has been developed in low melting L-(+)-tartaric acid–DMU melt mixtures. The functionalized hydantoins are obtained in good yields from β,γ-unsaturated ketoacids and urea under environmentally benign and simple reaction conditions.

Graphical abstract: Synthesis of substituted hydantoins in low melting mixtures

Supplementary files

Article information

Article type
Communication
Submitted
17 Feb 2013
Accepted
17 Apr 2013
First published
17 Apr 2013

Chem. Commun., 2013,49, 5052-5054

Synthesis of substituted hydantoins in low melting mixtures

S. Gore, K. Chinthapally, S. Baskaran and B. König, Chem. Commun., 2013, 49, 5052 DOI: 10.1039/C3CC41254G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements