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Issue 28, 2013
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Intracellular activation of acetyl-CoA by an artificial reaction promoter and its fluorescent detection

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Abstract

The application of a new rhodamine-based fluorescent probe, RH–NH23 and an acyl transfer promoter, PBu3, to Hela cells induced a time-dependent increase in fluorescence in the mitochondria, which was most likely due to acetylation of RH–NH23 with activated acetyl-CoA by the artificial reaction promoter in living cells.

Graphical abstract: Intracellular activation of acetyl-CoA by an artificial reaction promoter and its fluorescent detection

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Publication details

The article was received on 24 Jan 2013, accepted on 19 Feb 2013 and first published on 19 Feb 2013


Article type: Communication
DOI: 10.1039/C3CC40616D
Citation: Chem. Commun., 2013,49, 2876-2878
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    Intracellular activation of acetyl-CoA by an artificial reaction promoter and its fluorescent detection

    H. Komatsu, Y. Shindo, S. A. Kawashima, K. Yamatsugu, K. Oka and M. Kanai, Chem. Commun., 2013, 49, 2876
    DOI: 10.1039/C3CC40616D

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