Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development†
Abstract
As a guide for chemical probe design, focused analogue synthetic studies were undertaken upon the
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* Corresponding authors
a
Departments of Chemistry and Immunology and Microbial Science, The Skaggs Institute for Chemical Biology and The Worm Institute for Research and Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, USA
E-mail:
kdjanda@scripps.edu
Fax: +1 858-784-2595
Tel: +1 858-784-2515
b
Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, USA
E-mail:
vkrav@scripps.edu
Tel: +1 858-784-9170
As a guide for chemical probe design, focused analogue synthetic studies were undertaken upon the
A. L. Garner, J. Yu, A. K. Struss, G. F. Kaufmann, V. V. Kravchenko and K. D. Janda, Chem. Commun., 2013, 49, 1515 DOI: 10.1039/C3CC38851D
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