A reversible fluorescence probe based on Se–BODIPY for the redox cycle between HClO oxidative stress and H2S repair in living cells

Bingshuai Wang; Peng Li; Fabiao Yu; Ping Song; Xiaofei Sun; Songqiu Yang; Zhangrong Lou; Keli Han

doi:10.1039/C2CC37803E

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A reversible fluorescence probe based on Se–BODIPY for the redox cycle between HClO oxidative stress and H₂S repair in living cells†

Bingshuai Wang,^a Peng Li,^a Fabiao Yu,^a Ping Song,^a Xiaofei Sun,^a Songqiu Yang,^a Zhangrong Lou^a and Keli Han*^a

Author affiliations

* Corresponding authors

^a State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences (CAS), 457 Zhongshan Road, Dalian 116023, P. R. China
E-mail: klhan@dicp.ac.cn

Abstract

We have developed a new reversible fluorescence probe MPhSe–BOD for the redox cycle process between hypochlorous acid and hydrogen sulfide in solution and in living cells. Confocal microscopy imaging using RAW264.7 cell lines shows that the probe has good cell membrane permeability, and can monitor intracellular HClO/H₂S redox cycles continuously.

Download options Please wait...

Supplementary files

Supplementary information PDF (5607K)

Article information

DOI: https://doi.org/10.1039/C2CC37803E
Article type: Communication
Submitted: 27 Oct 2012
Accepted: 12 Dec 2012
First published: 12 Dec 2012

Download Citation

Chem. Commun., 2013,49, 1014-1016

Permissions

Request permissions

A reversible fluorescence probe based on Se–BODIPY for the redox cycle between HClO oxidative stress and H₂S repair in living cells

B. Wang, P. Li, F. Yu, P. Song, X. Sun, S. Yang, Z. Lou and K. Han, Chem. Commun., 2013, 49, 1014 DOI: 10.1039/C2CC37803E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications