Issue 2, 2013

An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

Abstract

An efficient single-enzymatic cascade approach for the asymmetric synthesis of chiral amines has been developed, which applies the amino donor 3-aminocyclohexa-1,5-dienecarboxylic acid spontaneously tautomerizing to reach reaction completion with excellent ee values.

Graphical abstract: An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

Supplementary files

Article information

Article type
Communication
Submitted
03 Oct 2012
Accepted
07 Nov 2012
First published
08 Nov 2012

Chem. Commun., 2013,49, 161-163

An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase

B. Wang, H. Land and P. Berglund, Chem. Commun., 2013, 49, 161 DOI: 10.1039/C2CC37232K

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