Issue 1, 2013
From the journal:

Chemical Communications

Formation of SERS active nanoparticle assemblies via specific carbohydrate–protein interactions†

Derek Craig,a   Jonathan Simpson,a   Karen Fauldsa  and  Duncan Graham*a  

* Corresponding authors

a Centre for Molecular Nanometrology, WestCHEM, Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, UK
E-mail: Duncan.graham@strath.ac.uk

Abstract

An on/off SERS aggregation system has been designed to investigate carbohydrate–lectin interactions. Detection of the lectin ConA was achieved at pico molar levels. Discrimination was also demonstrated between two different carbohydrate moieties demonstrating the specific interaction between the carbohydrate and specific protein present.

Graphical abstract: Formation of SERS active nanoparticle assemblies via specific carbohydrate–protein interactions

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Article information

DOI
https://doi.org/10.1039/C2CC36949D
Article type
Communication
Submitted
25 Sep 2012
Accepted
19 Oct 2012
First published
22 Oct 2012

Chem. Commun., 2013,49, 30-32

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Formation of SERS active nanoparticle assemblies via specific carbohydrate–protein interactions

D. Craig, J. Simpson, K. Faulds and D. Graham, Chem. Commun., 2013, 49, 30 DOI: 10.1039/C2CC36949D

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