Issue 100, 2012
From the journal:

Chemical Communications

Nanogold-based bio-bar codes for label-free immunosensing of proteins coupling with an in situ DNA-based hybridization chain reaction†

Jun Zhou,a   Mingdi Xu,a   Dianping Tang,*a   Zhuangqiang Gao,a   Juan Tanga  and  Guonan Chen*a  

* Corresponding authors

a MOE Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China
E-mail: dianping.tang@fzu.edu.cn
Fax: +86 591 22866135
Tel: +86 591 22866135

Abstract

A label-free, non-enzyme immunosensing strategy is designed for ultrasensitive electronic detection of disease-related proteins (carcinoembryonic antigen as a model) by using gold nanoparticle-based bio-bar codes and an in situ amplified DNA-based hybridization chain reaction.

Graphical abstract: Nanogold-based bio-bar codes for label-free immunosensing of proteins coupling with an in situ DNA-based hybridization chain reaction

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Article information

DOI
https://doi.org/10.1039/C2CC36820J
Article type
Communication
Submitted
19 Sep 2012
Accepted
01 Nov 2012
First published
01 Nov 2012

Chem. Commun., 2012,48, 12207-12209

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Nanogold-based bio-bar codes for label-free immunosensing of proteins coupling with an in situ DNA-based hybridization chain reaction

J. Zhou, M. Xu, D. Tang, Z. Gao, J. Tang and G. Chen, Chem. Commun., 2012, 48, 12207 DOI: 10.1039/C2CC36820J

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