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Issue 93, 2012
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Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel

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Abstract

Electrical current signatures of DNA adducts were investigated during immobilization of strands inside the membrane-bound α-hemolysin ion channel. The current blockages produced by these adducts were found to depend on both size and shape, providing insights into the DNA–protein interactions and the size limitation of bulky adducts to be translocated.

Graphical abstract: Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel

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Publication details

The article was received on 31 Aug 2012, accepted on 08 Oct 2012 and first published on 09 Oct 2012


Article type: Communication
DOI: 10.1039/C2CC36366F
Citation: Chem. Commun., 2012,48, 11410-11412
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    Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel

    N. An, H. S. White and C. J. Burrows, Chem. Commun., 2012, 48, 11410
    DOI: 10.1039/C2CC36366F

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