Issue 91, 2012
From the journal:

Chemical Communications

Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells†

Li Fan,a   Yue-Jun Fu,a   Qiao-Ling Liu,a   Dong-Tao Lu,a   Chuan Donga  and  Shao-Min Shuang*a  

* Corresponding authors

a College of Chemistry and Chemical Engineering, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, PR China
E-mail: smshuang@sxu.edu.cn
Fax: +86-531-7018842
Tel: +86-531-7011688

Abstract

Two novel vis-NIR pH probes based on styrylcyanine with acidic pH response are easily synthesized, which display large Stokes shift and high sensitivity. The significant colocalizations of two probes with LysoTracker Green DND-26 are achieved in C6 cells, suggesting potential application for imaging acidic organelles in live cells.

Graphical abstract: Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells

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Article information

DOI
https://doi.org/10.1039/C2CC35363F
Article type
Communication
Submitted
25 Jul 2012
Accepted
18 Sep 2012
First published
09 Oct 2012

Chem. Commun., 2012,48, 11202-11204

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Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells

L. Fan, Y. Fu, Q. Liu, D. Lu, C. Dong and S. Shuang, Chem. Commun., 2012, 48, 11202 DOI: 10.1039/C2CC35363F

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