Issue 71, 2012

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

Abstract

Using CuBr2 as an additive, the Pd-catalyzed intermolecular C–H–C–H cross-coupling between benzoxazoles and unactivated simple arenes has been developed. This protocol provides a straightforward approach for the biological activity of 2-arylbenzoxazole derivatives.

Graphical abstract: Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

Supplementary files

Article information

Article type
Communication
Submitted
13 Jun 2012
Accepted
14 Jul 2012
First published
16 Jul 2012

Chem. Commun., 2012,48, 8964-8966

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

G. Wu, J. Zhou, M. Zhang, P. Hu and W. Su, Chem. Commun., 2012, 48, 8964 DOI: 10.1039/C2CC34238C

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