Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Tuesday 19th September 2017 from 8.00am to 4.00pm (BST).

During this time our website performance may be temporarily affected. If you have any questions please use the feedback button available under our menu button. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 68, 2012
Previous Article Next Article

A lateral flow biosensor for detection of single nucleotide polymorphism by circular strand displacement reaction

Author affiliations

Abstract

A lateral flow biosensor for detection of single nucleotide polymorphism based on circular strand displacement reaction (CSDPR) has been developed. Taking advantage of high fidelity of T4 DNA ligase, signal amplification by CSDPR, and the optical properties of gold nanoparticles, this assay has reached a detection limit of 0.01 fM.

Graphical abstract: A lateral flow biosensor for detection of single nucleotide polymorphism by circular strand displacement reaction

Back to tab navigation

Supplementary files

Publication details

The article was received on 01 Jun 2012, accepted on 05 Jul 2012 and first published on 06 Jul 2012


Article type: Communication
DOI: 10.1039/C2CC33931E
Citation: Chem. Commun., 2012,48, 8547-8549
  •   Request permissions

    A lateral flow biosensor for detection of single nucleotide polymorphism by circular strand displacement reaction

    Z. Xiao, P. Lie, Z. Fang, L. Yu, J. Chen, J. Liu, C. Ge, X. Zhou and L. Zeng, Chem. Commun., 2012, 48, 8547
    DOI: 10.1039/C2CC33931E

Search articles by author

Spotlight

Advertisements