Issue 60, 2012
From the journal:

Chemical Communications

Magnetic response of mitochondria-targeted cancer cells with bacterial magnetic nanoparticles†

Jungin Choi,a   Jaeha Shin,b   Junghoon Leeabc  and  Misun Cha*c  

* Corresponding authors

a Interdisciplinary Program of Bioengineering, Seoul National University, San 56-1, Shinlim, Kwanak, Seoul, Korea

b Division of WCU Multiscale Mechanical Design, School of Mechanical and Aerospace Engineering, Seoul National University, Seoul, Korea

c Inter-university Semiconductor Research Center, Seoul National University, Seoul, Korea
E-mail: cmsbest@snu.ac.kr
Fax: +82-2-877-9104
Tel: +82-2-880-9101

Abstract

We first demonstrate the effects of magnetic trapping of mitochondria using aptamer conjugated to bacterial magnetic nanoparticles that allowed targeting of the mitochondrial cytochrome c in the treatment of cancer cells. Our findings offer a new approach for targeted cell therapy, with the advantage of remote control over subcellular elements.

Graphical abstract: Magnetic response of mitochondria-targeted cancer cells with bacterial magnetic nanoparticles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC33659F
Article type
Communication
Submitted
22 May 2012
Accepted
07 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 7474-7476

Permissions

Request permissions

Magnetic response of mitochondria-targeted cancer cells with bacterial magnetic nanoparticles

J. Choi, J. Shin, J. Lee and M. Cha, Chem. Commun., 2012, 48, 7474 DOI: 10.1039/C2CC33659F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements