Issue 65, 2012
From the journal:

Chemical Communications

Fully automated sequential solid phase approach towards viral RNA-nucleopeptides†‡

Gerbrand J. van der Heden van Noort,a   Pieter van Delft,a   Nico J. Meeuwenoord,a   Herman S. Overkleeft,a   Gijsbert A. van der Marel*a  and  Dmitri V. Filippov*a  

* Corresponding authors

a Leiden Institute of Chemistry, Leiden University, P. O. Box 9502, 2300 RA Leiden, The Netherlands
E-mail: marel_g@chem.leidenuniv.nl, filippov@chem.leidenuniv.nl

Abstract

The synthesis of two ribonucleoprotein fragments of unprecedented complexity is reported. These hybrid biomolecules are prepared combining the use of an automated solid phase peptide and oligonucleotide synthesizer on a single solid support.

Graphical abstract: Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

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Article information

DOI
https://doi.org/10.1039/C2CC33477A
Article type
Communication
Submitted
14 May 2012
Accepted
27 Jun 2012
First published
28 Jun 2012

Chem. Commun., 2012,48, 8093-8095

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Fully automated sequential solid phase approach towards viral RNA-nucleopeptides

G. J. van der Heden van Noort, P. V. Delft, N. J. Meeuwenoord, H. S. Overkleeft, G. A. van der Marel and D. V. Filippov, Chem. Commun., 2012, 48, 8093 DOI: 10.1039/C2CC33477A

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