Issue 52, 2012
From the journal:

Chemical Communications

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres†‡

Francesco Manoni,a   Claudio Cornaggia,a   James Murray,a   Sean Tallona  and  Stephen J. Connon*a  

* Corresponding authors

a School of Chemistry, Centre for Synthesis and Chemical Biology, Trinity Biomedical Sciences Institute, University of Dublin, Trinity College, Dublin 2, Ireland
E-mail: connons@tcd.ie
Fax: +35316712826

Abstract

A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.

Graphical abstract: Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

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Article information

DOI
https://doi.org/10.1039/C2CC32147E
Article type
Communication
Submitted
23 Mar 2012
Accepted
01 May 2012
First published
23 May 2012

Chem. Commun., 2012,48, 6502-6504

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Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

F. Manoni, C. Cornaggia, J. Murray, S. Tallon and S. J. Connon, Chem. Commun., 2012, 48, 6502 DOI: 10.1039/C2CC32147E

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