Issue 66, 2012
From the journal:

Chemical Communications

The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters†

Apeng Liang,ab   Xinjian Li,a   Dongfeng Liu,a   Jingya Li,b   Dapeng Zou,*ab   Yangjie Wua  and  Yusheng Wu*bc  

* Corresponding authors

a The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, PR China
E-mail: Dapeng.zou@tetranov.com
Fax: +86 371 6776 1837
Tel: +86 371 6776 1680

b Tetranov Biopharm, LLC, 75 Daxue Road, Zhengzhou, PR China

c Tetranov International, Inc., 100 Jersey Avenue, Suite A340, New Brunswick, USA
E-mail: yusheng.wu@tetranovglobal.com
Fax: +1 732 253 7327
Tel: +1 732 253 7326

Abstract

The cross-coupling reactions of 1,1,1-trifluoro-2-iodoethane with aryl and heteroaryl boronic acid esters have been successfully achieved. The new protocol allows for a convenient introduction of trifluoroethyl groups into a variety of aryl and heteroaryl moieties under mild conditions.

Graphical abstract: The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters

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Article information

DOI
https://doi.org/10.1039/C2CC31651J
Article type
Communication
Submitted
06 Mar 2012
Accepted
19 Jun 2012
First published
21 Jun 2012

Chem. Commun., 2012,48, 8273-8275

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The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters

A. Liang, X. Li, D. Liu, J. Li, D. Zou, Y. Wu and Y. Wu, Chem. Commun., 2012, 48, 8273 DOI: 10.1039/C2CC31651J

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