Issue 15, 2012

Immobilization-free screening of aptamers assisted by graphene oxide

Abstract

Graphene oxide (GO) has the ability to separate free short ssDNA in heterogeneous solution. This feature is applied as a label free platform for screening of aptamers that bind to their target with high affinity and specificity. Herein, we report an aptamer selection strategy for Nampt protein based on GO.

Graphical abstract: Immobilization-free screening of aptamers assisted by graphene oxide

Supplementary files

Article information

Article type
Communication
Submitted
18 Oct 2011
Accepted
23 Nov 2011
First published
24 Nov 2011

Chem. Commun., 2012,48, 2071-2073

Immobilization-free screening of aptamers assisted by graphene oxide

J. Park, R. Tatavarty, D. W. Kim, H. Jung and M. B. Gu, Chem. Commun., 2012, 48, 2071 DOI: 10.1039/C2CC16473F

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