Jump to main content
Jump to site search

Issue 5, 2012
Previous Article Next Article

Introducing chemiluminescence resonance energy transfer into immunoassay in a microfluidic format for an improved assay sensitivity

Author affiliations

Abstract

We report on a novel strategy to improve microfluidic immunoassay sensitivity by introducing chemiluminescence resonance energy transfer (CRET) into the immunoreactions. The proposed CRET-based immunoassay for estradiol (E2, as a model analyte) is one of the most sensitive immunoassay with a limit of detection at 3.6 × 10−11 M E2 in a microfluidic format.

Graphical abstract: Introducing chemiluminescence resonance energy transfer into immunoassay in a microfluidic format for an improved assay sensitivity

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Oct 2011, accepted on 20 Nov 2011 and first published on 21 Nov 2011


Article type: Communication
DOI: 10.1039/C1CC16435J
Citation: Chem. Commun., 2012,48, 699-701
  •   Request permissions

    Introducing chemiluminescence resonance energy transfer into immunoassay in a microfluidic format for an improved assay sensitivity

    S. Zhao, J. Liu, Y. Huang and Y. Liu, Chem. Commun., 2012, 48, 699
    DOI: 10.1039/C1CC16435J

Search articles by author

Spotlight

Advertisements