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Issue 5, 2012
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Label-free and sensitive thrombin sensing on a molecularly grafted aptamer on graphene

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Abstract

A unique nanocomposite was constructed by grafting an aptamer on graphene and used as a label-free biosensor for thrombin sensing, showing good selectivity, a low detection limit of 0.45 fM and high sensitivity, with a linear response up to 100 fM.

Graphical abstract: Label-free and sensitive thrombin sensing on a molecularly grafted aptamer on graphene

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Publication details

The article was received on 01 Sep 2011, accepted on 09 Nov 2011 and first published on 25 Nov 2011


Article type: Communication
DOI: 10.1039/C1CC15429J
Citation: Chem. Commun., 2012,48, 738-740
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    Label-free and sensitive thrombin sensing on a molecularly grafted aptamer on graphene

    Y. Wang, Y. Xiao, X. Ma, N. Li and X. Yang, Chem. Commun., 2012, 48, 738
    DOI: 10.1039/C1CC15429J

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