Issue 25, 2011

9G DNAChip: microarray based on the multiple interactions of 9 consecutive guanines

Abstract

We introduce the phenomenon of molecular recognition to immobilize oligonucleotides on AMCA slides for the production of 9G DNAChips. Facile and efficient method for the immobilization of the oligonucleotides appended with consecutive nine guanine bases is described. The 9G DNAChips shows more than 90% hybridization efficiency at 25 °C in 30 min.

Graphical abstract: 9G DNAChip: microarray based on the multiple interactions of 9 consecutive guanines

Supplementary files

Article information

Article type
Communication
Submitted
28 Apr 2011
Accepted
06 May 2011
First published
27 May 2011
This article is Open Access

Chem. Commun., 2011,47, 7101-7103

9G DNAChip: microarray based on the multiple interactions of 9 consecutive guanines

K. Song, S. Balasaheb Nimse, J. Kim, J. Kim, V. Nguyen, V. Ta and T. Kim, Chem. Commun., 2011, 47, 7101 DOI: 10.1039/C1CC12489G

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