Issue 19, 2011
From the journal:

Chemical Communications

A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex formation†

Chuanqi Zhao,ab   Li Wu,ab   Jinsong Rena  and  Xiaogang Qu*a  

* Corresponding authors

a Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China
E-mail: xqu@ciac.jl.cn

b Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China

Abstract

A facile and general label-free assay for sensitive and selective DNA detection has been developed based on enzyme amplification and ligand-responsive quadruplex formation.

Graphical abstract: A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex formation

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Article information

DOI
https://doi.org/10.1039/C1CC11396H
Article type
Communication
Submitted
10 Mar 2011
Accepted
28 Mar 2011
First published
11 Apr 2011

Chem. Commun., 2011,47, 5461-5463

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A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex formation

C. Zhao, L. Wu, J. Ren and X. Qu, Chem. Commun., 2011, 47, 5461 DOI: 10.1039/C1CC11396H

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