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Issue 29, 2011
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A water-soluble perylene dye functionalised with a 17β-estradiol: a new fluorescent tool for steroid hormones

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Abstract

We have successfully been able to synthesise a specific estrogen receptor-directed biolabel based on a fluorescent water-soluble perylenebisimide, thus offering great potential for determining the presence of estrogen receptors in any kind of cell. Moreover, this synthetic strategy allows the preparation of other conjugates involved in the study of any kind of receptor, simply by selecting the appropriate agonist or antagonist.

Graphical abstract: A water-soluble perylene dye functionalised with a 17β-estradiol: a new fluorescent tool for steroid hormones

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Publication details

The article was received on 18 Feb 2011, accepted on 31 May 2011 and first published on 20 Jun 2011


Article type: Communication
DOI: 10.1039/C1CC10966A
Citation: Chem. Commun., 2011,47, 8307-8309
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    A water-soluble perylene dye functionalised with a 17β-estradiol: a new fluorescent tool for steroid hormones

    F. J. Céspedes-Guirao, A. B. Ropero, E. Font-Sanchis, Á. Nadal, F. Fernández-Lázaro and Á. Sastre-Santos, Chem. Commun., 2011, 47, 8307
    DOI: 10.1039/C1CC10966A

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