Issue 19, 2011
From the journal:

Chemical Communications

Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition†

Shan Xu,a   Juyou Lua  and  Hua Fu*a  

* Corresponding authors

a Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China
E-mail: fuhua@mail.tsinghua.edu.cn
Fax: 86 10 62781695
Tel: 86 10 62797186

Abstract

A convenient and efficient copper-catalyzed cascade method has been developed for the synthesis of benzimidazoquinazoline derivatives via reactions of readily available substituted 2-(2-halophenyl)benzoimidazoles with amidines or guanidine under mild conditions (even at room temperature).

Graphical abstract: Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition

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Article information

DOI
https://doi.org/10.1039/C1CC10383K
Article type
Communication
Submitted
20 Jan 2011
Accepted
07 Mar 2011
First published
01 Apr 2011

Chem. Commun., 2011,47, 5596-5598

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Copper-catalyzed cascade synthesis of benzimidazoquinazoline derivatives under mild condition

S. Xu, J. Lu and H. Fu, Chem. Commun., 2011, 47, 5596 DOI: 10.1039/C1CC10383K

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