Issue 15, 2011
From the journal:

Chemical Communications

Bodipy-diacrylate imaging probes for targeted proteins inside live cells†

Jae-Jung Lee,a   Sung-Chan Lee,a   Duanting Zhai,b   Young-Hoon Ahn,c   Hui Yun Yeo,a   Yee Ling Tana  and  Young-Tae Chang*ab  

* Corresponding authors

a Laboratory of Bioimaging Probe Development, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore 138667, Singapore

b Department of Chemistry, National University of Singapore 3 Science Drive 3, Singapore 117543, MedChem Program of Life Sciences Institute, National University of Singapore, , Singapore
E-mail: chmcyt@nus.edu.sg

c Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, USA

Abstract

A bodipy probe was developed for site-specific labeling of tagged proteins inside live cells which displays a large spectral change upon covalent coupling to the designed peptide that contains two pairs of Arg-Cys.

Graphical abstract: Bodipy-diacrylate imaging probes for targeted proteins inside live cells

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Article information

DOI
https://doi.org/10.1039/C1CC10362H
Article type
Communication
Submitted
19 Jan 2011
Accepted
16 Feb 2011
First published
08 Mar 2011

Chem. Commun., 2011,47, 4508-4510

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Bodipy-diacrylate imaging probes for targeted proteins inside live cells

J. Lee, S. Lee, D. Zhai, Y. Ahn, H. Y. Yeo, Y. L. Tan and Y. Chang, Chem. Commun., 2011, 47, 4508 DOI: 10.1039/C1CC10362H

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