Issue 18, 2011

A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction

Abstract

An ultra-sensitive, fast, simple and easily operated method for sequence-specific detection of polynucleotides is proposed herein, which is based on a novel target-triggered isothermal exponential degradation reaction (TT-isoTexpDR) and the color change of probe-functionalized gold nanoparticles.

Graphical abstract: A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction

Supplementary files

Article information

Article type
Communication
Submitted
11 Jan 2011
Accepted
16 Mar 2011
First published
29 Mar 2011

Chem. Commun., 2011,47, 5262-5264

A new strategy for a DNA assay based on a target-triggered isothermal exponential degradation reaction

J. Zhao, T. Liu, Q. Fan and G. Li, Chem. Commun., 2011, 47, 5262 DOI: 10.1039/C1CC10186B

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