Issue 18, 2010
From the journal:

Chemical Communications

Fluorescence detection for DNA using hybridization chain reaction with enzyme-amplification†

Shuyan Niu,a   Yu Jianga  and  Shusheng Zhang*a  

* Corresponding authors

a Key Laboratory of Eco-chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, Shandong, P. R. China
E-mail: shushzhang@126.com
Fax: (+86) 532-84022750
Tel: (+86) 532-84022750

Abstract

A signal amplification based on a combination of hybridization chain reaction (HCR) and enzyme-enhancement was applied in the study of a novel biosensor. The target sequence was added as catalyst which was simply transmitted but did not disappear as the DNA double strand grew on the surface of magnetic beads (MBs).

Graphical abstract: Fluorescence detection for DNA using hybridization chain reaction with enzyme-amplification

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Article information

DOI
https://doi.org/10.1039/C000166J
Article type
Communication
Submitted
06 Jan 2010
Accepted
03 Mar 2010
First published
20 Mar 2010

Chem. Commun., 2010,46, 3089-3091

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Fluorescence detection for DNA using hybridization chain reaction with enzyme-amplification

S. Niu, Y. Jiang and S. Zhang, Chem. Commun., 2010, 46, 3089 DOI: 10.1039/C000166J

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