Templated display of biomolecules and inorganic nanoparticles by metal ion-induced peptide nanofibers

Byoung-Chul Lee; Ronald N. Zuckermann

doi:10.1039/B925395E

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Templated display of biomolecules and inorganic nanoparticles by metal ion-induced peptide nanofibers†

Byoung-Chul Lee^a and Ronald N. Zuckermann*^a

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* Corresponding authors

^a Biological Nanostructures Facility, The Molecular Foundry, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd., Berkeley, USA
E-mail: rnzuckermann@lbl.gov
Fax: +1 510-495-2376
Tel: +1 510-486-7091

Abstract

We functionalized peptide nanofibers to provide a nano-scale template for the display of biomolecules and inorganic nanoparticles using metal ion coordination. Nanofibers assembled only in the presence of certain divalent metal ions, and could be readily dissolved by a metal-chelating reagent, EDTA.

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Supplementary files

Materials and methods, scanning electron microscopy images, X-ray power diffraction data, binding of mCherry to the metal-ion induced fibers, binding of mCherry (lacking his6 tag) to the fibers, size distribution of Cu and Ni nanoparticles, and high-resolution TEM images of the metal nanoparticles PDF (1732K)

Article information

DOI: https://doi.org/10.1039/B925395E
Article type: Communication
Submitted: 01 Dec 2009
Accepted: 19 Jan 2010
First published: 03 Feb 2010

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Chem. Commun., 2010,46, 1634-1636

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Templated display of biomolecules and inorganic nanoparticles by metal ion-induced peptide nanofibers

B. Lee and R. N. Zuckermann, Chem. Commun., 2010, 46, 1634 DOI: 10.1039/B925395E

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Chemical Communications

Templated display of biomolecules and inorganic nanoparticles by metal ion-induced peptide nanofibers†

Abstract

Supplementary files

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Templated display of biomolecules and inorganic nanoparticles by metal ion-induced peptide nanofibers

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