Combined CuI-catalysed alkyne–azidecycloaddition and furan–maleimide Diels–Alder “click” chemistry approach to thermoresponsive dendrimers

Abstract

A divergent dendrimer construction methodology that employs Cu^I-catalysed alkyne–azidecycloaddition (CuAAC) and furan–maleimide Diels–Alder (DA) “click” chemistry in a layer-by-layer fashion, is described. This synergisitic approach yields dendrimers that undergo thermal disassembly via a retro-DA reaction.