Issue 4, 2010
From the journal:

Chemical Communications

Trityl-nitroxide biradicals as unique molecular probes for the simultaneous measurement of redox status and oxygenation†

Yangping Liu,a   Frederick A. Villamena,ab   Antal Rockenbauerc  and  Jay L. Zweier*a  

* Corresponding authors

a Center for Biomedical EPR Spectroscopy and Imaging, The Davis Heart and Lung Research Institute, The Division of Cardiovascular Medicine, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, USA
E-mail: Jay.Zweier@osumc.edu
Fax: +1 614-247-7845
Tel: +1 614-247-7788

b Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, USA

c Chemical Research Center, Institute of Structural Chemistry, P.O. Box 17, H-1525 Budapest, Hungary

Abstract

Novel trityl-nitroxide biradicals were synthesized and exhibited enhanced sensitivity and stability for rapid and simultaneous measurement of redox status and oxygenation by electron paramagnetic resonance spectroscopy.

Graphical abstract: Trityl-nitroxide biradicals as unique molecular probes for the simultaneous measurement of redox status and oxygenation

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Article information

DOI
https://doi.org/10.1039/B919279D
Article type
Communication
Submitted
17 Sep 2009
Accepted
02 Nov 2009
First published
18 Nov 2009

Chem. Commun., 2010,46, 628-630

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Trityl-nitroxide biradicals as unique molecular probes for the simultaneous measurement of redox status and oxygenation

Y. Liu, F. A. Villamena, A. Rockenbauer and J. L. Zweier, Chem. Commun., 2010, 46, 628 DOI: 10.1039/B919279D

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