Issue 48, 2009
From the journal:

Chemical Communications

Glutathione-bound gold nanoclusters for selective-binding and detection of glutathione S-transferase-fusion proteins from cell lysates†

Cheng-Tai Chen,a   Wei-Jen Chen,a   Chao-Zong Liu,b   Ling-Ya Changb  and  Yu-Chie Chen*a  

* Corresponding authors

a Department of Applied Chemistry, National Chiao Tung University, Hsinchu 300, Taiwan
E-mail: yuchie@mail.nctu.edu.tw
Fax: 886-3-5723764
Tel: 886-3-5131527

b Department of Pharmacology and Institute of Pharmacology & Toxicology, Tzu Chi University, Hualien 970, Taiwan

Abstract

A straightforward method for the rapid detection of the presence of glutathione S-transferase (GST)-tagged proteins from sample solutions using glutathione (GSH)-bound gold nanoclusters (Au@GSH NCs) with luminescence properties as the detection probes by simple observation with the naked eye was proposed in this study.

Graphical abstract: Glutathione-bound gold nanoclusters for selective-binding and detection of glutathione S-transferase-fusion proteins from cell lysates

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Article information

DOI
https://doi.org/10.1039/B916919A
Article type
Communication
Submitted
17 Aug 2009
Accepted
19 Oct 2009
First published
03 Nov 2009

Chem. Commun., 2009, 7515-7517

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Glutathione-bound gold nanoclusters for selective-binding and detection of glutathione S-transferase-fusion proteins from cell lysates

C. Chen, W. Chen, C. Liu, L. Chang and Y. Chen, Chem. Commun., 2009, 7515 DOI: 10.1039/B916919A

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