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The design, synthesis and evaluation of hypoxia-activated pro-oligonucleotides

Nan Zhang,ab   Chunyan Tan,a   Puqin Cai,a   Peizhuo Zhang,c   Yufen Zhaob and   Yuyang Jiang*ad  
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Corresponding authors
a
Key Laboratory of Chemical Biology, Guangdong Province, Graduate School at Shenzhen, Tsinghua University, Shenzhen, P.R. China
E-mail: jiangyy@sz.tsinghua.edu.cn
b
Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, P.R. China
c
Shanghai GenePharma Co. Ltd, 1011 Halley Road, Z.-J. High Tech Park, Shanghai, P.R. China
d
School of Medicine, Tsinghua University, Beijing, P.R. China
Chem. Commun., 2009, 3216-3218

DOI: 10.1039/B903331A
Received 17 Feb 2009, Accepted 27 Mar 2009
First published online 23 Apr 2009
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