Issue 48, 2008
From the journal:

Chemical Communications

Pyridine-based lanthanidecomplexes: towards bimodal agents operating as near infrared luminescent and MRI reporters†

Laurent Pellegatti,ab   Jian Zhang,c   Bohuslav Drahos,a   Sandrine Villette,a   Franck Suzenet,b   Gérald Guillaumet,b   Stéphane Petoud*ac  and  Éva Tóth*a  

* Corresponding authors

a Centre de Biophysique Moléculaire, CNRS, rue Charles Sadron, France
E-mail: eva.jakabtoth@cnrs-orleans.fr
Fax: +33 2 38 63 15 17
Tel: +33 2 38 25 76 25

b Institut de Chimie Organique et Analytique, UMR 6005 CNRS/Université d’Orléans, Rue de Chartres, France

c Dept. of Chemistry, The University of Pittsburgh, 219 Parkman Avenue, USA
E-mail: spetoud@pitt.edu

Abstract

We report two prototype Ln3+complexes that address requirements for both MRI and luminescence imaging and we demonstrate that the presence of two H2O molecules bound to the Ln3+, beneficial for MRI applications of the Gd3+ analogue, is not a major limitation for the development of NIR luminescent agents.

Graphical abstract: Pyridine-based lanthanidecomplexes: towards bimodal agents operating as near infrared luminescent and MRI reporters

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Article information

DOI
https://doi.org/10.1039/B817343E
Article type
Communication
Submitted
02 Oct 2008
Accepted
23 Oct 2008
First published
12 Nov 2008

Chem. Commun., 2008, 6591-6593

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Pyridine-based lanthanidecomplexes: towards bimodal agents operating as near infrared luminescent and MRI reporters

L. Pellegatti, J. Zhang, B. Drahos, S. Villette, F. Suzenet, G. Guillaumet, S. Petoud and É. Tóth, Chem. Commun., 2008, 6591 DOI: 10.1039/B817343E

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