Issue 43, 2008

A genetic selection system for evolving enantioselectivity of enzymes

Abstract

As an alternative to screening in the directed evolution of enantioselective enzymes, a selection system has been implemented for a lipase-catalyzed hydrolytic kinetic resolution of a chiral ester.

Graphical abstract: A genetic selection system for evolving enantioselectivity of enzymes

Supplementary files

Article information

Article type
Communication
Submitted
20 Aug 2008
Accepted
03 Sep 2008
First published
22 Sep 2008

Chem. Commun., 2008, 5502-5504

A genetic selection system for evolving enantioselectivity of enzymes

M. T. Reetz, H. Höbenreich, P. Soni and L. Fernández, Chem. Commun., 2008, 5502 DOI: 10.1039/B814538E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements