Issue 48, 2008
From the journal:

Chemical Communications

Kinetics of base stacking-aided DNAhybridization†

Bi-feng Yuan,‡ab   Xing-ying Zhuang,b   Yu-hua Haoa  and  Zheng Tan*ab  

* Corresponding authors

a State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
E-mail: z.tan@ioz.ac.cn, tanclswu@public.wh.hb.cn

b Laboratory of Biochemistry and Biophysics, College of Life Sciences, Wuhan University, Wuhan, China

Abstract

The association and dissociation rate constants (ka and kd) of DNAhybridizations involving dual, single or no stacking with different base-pairing sizes were measured, which reveals the advantage of stacking hybridization in both the kinetic and steady state.

Graphical abstract: Kinetics of base stacking-aided DNAhybridization

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Article information

DOI
https://doi.org/10.1039/B812929K
Article type
Communication
Submitted
28 Jul 2008
Accepted
14 Oct 2008
First published
12 Nov 2008

Chem. Commun., 2008, 6600-6602

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Kinetics of base stacking-aided DNAhybridization

B. Yuan, X. Zhuang, Y. Hao and Z. Tan, Chem. Commun., 2008, 6600 DOI: 10.1039/B812929K

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