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Issue 46, 2008
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Rational design of an optical adenosine sensor by conjugating a DNA aptamer with split DNAzyme halves

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Abstract

Split halves of a hemin-binding DNAzyme have been assembled with an anti-adenosine aptamer to build a homogeneous allosteric sensor for adenosine with high selectivity and sensitivity.

Graphical abstract: Rational design of an optical adenosine sensor by conjugating a DNA aptamer with split DNAzyme halves

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Publication details

The article was received on 26 Jun 2008, accepted on 22 Sep 2008, published on 16 Oct 2008 and first published online on 16 Oct 2008


Article type: Communication
DOI: 10.1039/B810812A
Citation: Chem. Commun., 2008, 6161-6163
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    Rational design of an optical adenosine sensor by conjugating a DNA aptamer with split DNAzyme halves

    N. Lu, C. Shao and Z. Deng, Chem. Commun., 2008, 6161
    DOI: 10.1039/B810812A

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