Issue 40, 2008
From the journal:

Chemical Communications

Recognition of lectin with a high signal to noise ratio: carbohydrate-tri(ethylene glycol)-alkanethiol co-adsorbed monolayer†

Yukari Sato,*a   Kyoko Yoshioka,a   Mutsuo Tanaka,a   Teiichi Murakami,a   Miho Neide Ishidaa  and  Osamu Niwaa  

* Corresponding authors

a National Institute of Advanced Industrial Science and Technology (AIST), Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki, Japan
E-mail: yukari-sato@aist.go.jp
Fax: +81-29-861-6177
Tel: +81-29-861-6158

Abstract

Densely packed co-adsorbed ultrathin mono molecular layers of short tri(ethylene glycol)-alkanethiolate (for repelling proteins) and maltoside terminated alkanethiolate (for capturing lectin) provided an extremely high signal to noise ratio surface: the repelling molecules, which had two different functions (highly flexible-hydrophilic arm and rigid packing tail group), worked as “nano barriers” in the recognition monolayer.

Graphical abstract: Recognition of lectin with a high signal to noise ratio: carbohydrate-tri(ethylene glycol)-alkanethiol co-adsorbed monolayer

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Article information

DOI
https://doi.org/10.1039/B809481K
Article type
Communication
Submitted
04 Jun 2008
Accepted
04 Aug 2008
First published
09 Sep 2008

Chem. Commun., 2008, 4909-4911

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Recognition of lectin with a high signal to noise ratio: carbohydrate-tri(ethylene glycol)-alkanethiol co-adsorbed monolayer

Y. Sato, K. Yoshioka, M. Tanaka, T. Murakami, M. N. Ishida and O. Niwa, Chem. Commun., 2008, 4909 DOI: 10.1039/B809481K

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