Issue 5, 2007
From the journal:

Chemical Communications

A “hidden” co-crystal of caffeine and adipic acid†

Dejan-Krešimir Bučar,ab   Rodger F. Henry,c   Xiaochun Lou,a   Thomas B. Borchardtd  and  Geoff G. Z. Zhang*a  

* Corresponding authors

a Solid State Sciences, Global Pharmaceutical R&D, Abbott Laboratories, North Chicago, IL, USA
E-mail: Geoff.GZ.Zhang@abbott.com
Fax: 1- 847-937-2417
Tel: 1-847-937-4702

b Department of Chemistry, University of Iowa, Iowa City, IA, USA

c Structural Chemistry, Global Pharmaceutical R&D, Abbott Laboratories, Abbott Park, IL, USA

d Solid State Chemistry, Global Pharmaceutical R&D, Abbott Laboratories, North Chicago, IL, USA

Abstract

Co-crystal formation between caffeine and adipic acid has been explored over the years without success; utilizing the newly developed co-crystal screening method, we have finally discovered this “hidden” caffeine and adipic acid co-crystal.

Graphical abstract: A “hidden” co-crystal of caffeine and adipic acid

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B611749J
Article type
Communication
Submitted
18 Aug 2006
Accepted
21 Nov 2006
First published
02 Jan 2007

Chem. Commun., 2007, 525-527

Permissions

Request permissions

A “hidden” co-crystal of caffeine and adipic acid

D. Bučar, R. F. Henry, X. Lou, T. B. Borchardt and G. G. Z. Zhang, Chem. Commun., 2007, 525 DOI: 10.1039/B611749J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements