Issue 2, 2007
From the journal:

Chemical Communications

Tandem Staudinger–azaWittig mediated ring expansion: rapid access to new isofagomine-tetrahydroxyazepane hybrids†

Hongqing Li,‡a   Yongmin Zhang,a   Pierre Vogel,b   Pierre Sinaÿa  and  Yves Blériot*a  

* Corresponding authors

a Ecole Normale Supérieure, Département de Chimie, UMR 8642, Université Pierre et Marie Curie-Paris 6, 75005 Paris; Institut de Chimie Moléculaire (FR 2769), 24 rue Lhomond, Paris Cedex 05, France
E-mail: yves.bleriot@ens.fr

b Laboratoire de glycochimie et de synthèse asymétrique, Swiss Federal Institute of Technology (EPFL) BCH, Lausanne-Dorigny, Switzerland

Abstract

New seven-membered iminosugars with potent and selective inhibition towards glycosidases have been prepared as 1-N-iminosugar homologues via a tandem Staudinger–azaWittig mediated ring expansion.

Graphical abstract: Tandem Staudinger–azaWittig mediated ring expansion: rapid access to new isofagomine-tetrahydroxyazepane hybrids

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Article information

DOI
https://doi.org/10.1039/B610377D
Article type
Communication
Submitted
21 Jul 2006
Accepted
10 Oct 2006
First published
24 Oct 2006

Chem. Commun., 2007, 183-185

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Tandem Staudinger–azaWittig mediated ring expansion: rapid access to new isofagomine-tetrahydroxyazepane hybrids

H. Li, Y. Zhang, P. Vogel, P. Sinaÿ and Y. Blériot, Chem. Commun., 2007, 183 DOI: 10.1039/B610377D

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