Issue 28, 2006

Convenient synthesis of electron-donating substituted benzonitriles by photolysis of phenyl halides and esters

Abstract

Irradiation of electron-donating substituted phenyl halides (fluorides and chlorides) or esters (mesylates, triflates and phosphates) in aqueous MeCN in the presence of KCN gives the corresponding benzonitriles in 48 to 100% yield through an ArSN1 reaction with the intermediacy of a triplet phenyl cation.

Graphical abstract: Convenient synthesis of electron-donating substituted benzonitriles by photolysis of phenyl halides and esters

Supplementary files

Article information

Article type
Communication
Submitted
21 Apr 2006
Accepted
19 May 2006
First published
08 Jun 2006

Chem. Commun., 2006, 3001-3003

Convenient synthesis of electron-donating substituted benzonitriles by photolysis of phenyl halides and esters

V. Dichiarante, M. Fagnoni and A. Albini, Chem. Commun., 2006, 3001 DOI: 10.1039/B605732B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements