Issue 22, 2006
From the journal:

Chemical Communications

Sugar–thioacetamide backbone in oligodeoxyribonucleosides for specific recognition of nucleic acids†

Khirud Gogoi,a   Anita D. Gunjala  and  Vaijayanti A. Kumar*a  

* Corresponding authors

a Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, India
E-mail: va.kumar@ncl.res.in
Fax: +91 20 25602623
Tel: +91 20 25602623

Abstract

The amide linkage being shorter than the natural phosphate linkage, an additional atom is introduced into oligodeoxyribonucleosides (ODNs) with sugar–thioacetamide backbone that show very good RNA recognition properties.

Graphical abstract: Sugar–thioacetamide backbone in oligodeoxyribonucleosides for specific recognition of nucleic acids

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Article information

DOI
https://doi.org/10.1039/B603958H
Article type
Communication
Submitted
16 Mar 2006
Accepted
04 Apr 2006
First published
25 Apr 2006

Chem. Commun., 2006, 2373-2375

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Sugar–thioacetamide backbone in oligodeoxyribonucleosides for specific recognition of nucleic acids

K. Gogoi, A. D. Gunjal and V. A. Kumar, Chem. Commun., 2006, 2373 DOI: 10.1039/B603958H

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