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Issue 36, 2005
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Design and synthesis of artificial phospholipid for selective cleavage of integral membrane protein

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Abstract

An artificial phospholipid, possessing saturated alkyl chains as a membrane anchor and protein recognition site as well as an Fe(III)–EDTA moiety as a protein cleavable polar head group, was designed and synthesized based on the amidite method for the purpose of examination of cleavage of integral membrane proteins.

Graphical abstract: Design and synthesis of artificial phospholipid for selective cleavage of integral membrane protein

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Publication details

The article was received on 06 Jun 2005, accepted on 29 Jul 2005 and first published on 17 Aug 2005


Article type: Communication
DOI: 10.1039/B507917A
Citation: Chem. Commun., 2005, 4575-4577
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    Design and synthesis of artificial phospholipid for selective cleavage of integral membrane protein

    T. Furuta, M. Sakai, H. Hayashi, T. Asakawa, F. Kataoka, S. Fujii, T. Suzuki, Y. Suzuki, K. Tanaka, N. Fishkin and K. Nakanishi, Chem. Commun., 2005, 4575
    DOI: 10.1039/B507917A

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